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Research published in the British Journal of Pharmacology demonstrated that molecular conjugation of B12 (specifically the corrin ring structure found in cyanocobalamin) with GLP-1 receptor agonists produced a compound that was not as readily absorbed into the brainstem areas responsible for triggering nausea

(2013) Pernicious Anemia: For Patients and Visitors Penn Medicine (2022) How to choose the right B12 for you. MTHFR Support Australia (2010-) Randomized, Placebo-Controlled Trial of Methyl B12 for Children with Autism. Journal of Child and Adolescent Psychopharmacology

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non-pregnant females) on metformin therapy ( 1000 mg/day) for more than 4 months and have vitamin B12 level 200 pg/mL)