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Uchida, H

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1 Introduction Vitamin B12, or cobalamin, is a water-soluble vitamin, that plays an essential role in cellular metabolism, particularly in DNA synthesis, methylation processes, and mitochondrial functions ( Lactobacillus spp ) ( Clinically overt vitamin B12 deficiency, characterized by hematological and neurological dysfunctions, is relatively uncommon

In the transcription factor pathway, H 2 O 2 regulates the activity of transcription factors, including NF-B, AP-1, HIF-1, and FOXO3 [82, 83], altering gene expression and promoting apoptosis