The compound's half-life is long enough that you'll maintain plasma levels, but the gastric effect peaks and wanes in a predictable curve
[3] Other common adverse effects reported during the clinical trials include back pain, upper respiratory tract infections, melanocyte naevus, decreased appetite, migraine, dizziness, weakness, fatigue, lethargy, sleepiness, hot flashes, abdominal pain, diarrhea, vomiting, flushing, development of warts, spots, and freckles, and itchy skin (between 1% and 10% of people)
In the pancreas, they stimulate glucose-dependent insulin secretion, meaning insulin is released only when blood glucose levels are elevated, which reduces the risk of hypoglycemia compared to some other diabetes medications
[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Martin E, Senders JT, DiRisio AC, Smith TR, Broekman MLD