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[25] In animal models, NAD+ repletion significantly increased lifespan, delayed the beginning of accelerated aging, and increased the number of proliferating stem cells in the germ line

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The volume of diluent (D5W or 0.45% sodium chloride) needed to be adjusted based on weight to avoid fluid overload, and hyponatremia: 520 kg: 3 mL/kg 5% dextrose in water infused over 60 min

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