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Passage of bile acids through the enterocyte activates FXR, which promotes the synthesis of fibroblast growth factor 19 (FGF19), which also circulates through the portal vein to the liver where it activates fibroblast growth factor-receptor 4 resulting in inhibition of bile acid synthesis

MC1R drives melanogenesis and tanning, MC3R and MC4R regulate sexual arousal and appetite, and MC5R modulates sebaceous gland activity

Potential Research Applications: Sleep and circadian rhythm studies Antioxidant and oxidative stress research Immune modulation investigations Neuroprotection and anti-aging models MT-2 (Melanotan 2) 10mg Melanotan II (MT-2) MT-2 (Melanotan 2) 10mg (Lyophilized Peptide) For Research Use Only Melanotan 2 (MT-2) is a synthetic analog of the alpha-melanocyte-stimulating hormone (-MSH), studied for its ability to activate melanocortin receptors involved in skin pigmentation, appetite regulation, and sexual function