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One has to be very clear that the situation might be different in foetal and neonatal mouse cardiomyocytes

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But a number in the safety data spooked a few of us that were paying extra attention to the details: Dysesthesia occurred in 20.9% of participants on the 12 mg dose

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Budhiraja P, Reddy KS, Butterfield RJ, Jadlowiec CC, Moss AA, Khamash HA, Kodali L, Misra SS, Heilman RL

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Pharmacokinetics and Safety of Long-Acting Release Formulations of Pasireotide (SOM230) in a Male Population: An Open-Label, Phase I Study

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