Therefore, LL-37 gets tightly attached to bacteria, and the peptide inserts itself into the lipid bilayer and disrupts its structure, causing the membrane to leak essential ions and metabolites, leading to rapid cell death
Yoopan N, Watcharasit P, Wongsawatkul O, Piyachaturawat P, Satayavivad J
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Interestingly, increased reliance on mitochondrial metabolism to exit the quiescent state is also associated with significant alterations to the morphology, mass, distribution, and overall membrane potential of the mitochondrial network ( FIGURE 2 Along with glycolysis and mitochondrial bioenergetics, lipogenesis and fatty acid mobilization from lipid droplets have also been shown to play a key role in NSC/NPC fate determination