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Oral products made with conjugated or esterified estrogens contain multiple estrogens, including E1 and E2, that are derived from horses (Premarin and Menest) or are synthetic and are not bioidentical

Biochemistry 64 , 44774486 (2025)

Ergotism is extremely rare today, primarily because the normal grain cleaning and milling processes remove most of the ergot so that only very low levels of alkaloids remain in the resultant flours