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IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is a modified analog of human IGF-1 with significantly extended half-life, studied for its anabolic and metabolic effects [1]

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The regular vitamin D metabolic profiles illustrated with either wild-type mouse VDR or VDR null mice transgenic for the wild-type human VDR, but not the ligand binding-defective form of the protein, this suggests the essential roles of VDR on VD metabolism 25