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Additionally, a family of enzymes expressed on the outer membrane of cells, gamma-glutamyl transpeptidases (GGTs), is involved in recycling extracellular glutathione, thereby contributing to de novo intracellular glutathione biosynthesis and ROS detoxification [14]

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Regarding long-term health and development, though available data is limited, cardiovascular and metabolic risk factors that may ultimately result in chronic cardiometabolic disease have been indicated 42

At the cellular level, GHK-Cu has been shown to increase collagen synthesis in fibroblast cultures by stimulating TGF- signaling and upregulating collagen type I and III gene expression