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It's the astrocytes and the microglia, and there are probably also some T cells that have the GLP-1 receptor that could be important
2021 Jan;12(1):143-157
Who Should Not Use GLP-1 Medications According to standard clinical guidelines and prescribing information, GLP-1 medications may not be appropriate for individuals who: Have a personal or family history of medullary thyroid carcinoma Have multiple endocrine neoplasia syndrome type 2 Have a history of pancreatitis Have severe gastrointestinal disease (gastroparesis, inflammatory bowel disease) Are pregnant, planning to become pregnant, or breastfeeding Have a history of severe allergic reactions to semaglutide, tirzepatide, or any inactive ingredients This is not a replacement for prescribed medical treatment for any health condition
This effect of GLP-1RAs may involve increased thermogenesis and modulation of mitochondrial function in various tissues
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