Foods rich in ellagitannins or ellagic acid If urolithin A sounds like something youre interested in, but you dont want to add another supplement to your daily regimen, then eating foods rich in its precursors could be an option.11 While ellagitannins and ellagic acid can be found in an array of fruits and nuts, the pomegranate fruit (and especially pomegranate juice) is often considered to be their best source.54 Unfortunately, this alternative only has the potential to work if youre part of the roughly 40% or so of people who can produce urolithin A after consuming these polyphenols (this depends on factors like your unique microbiome).6 And, currently, the only way to potentially find out if youre a producer or not is to apply for the Mitopure Challenge offered by Timeline
Lancet 366:17191724 Braune J, Weyer U, Hobusch C, Mauer J, Brning JC, Bechmann I, Gericke M (2017) IL-6 regulates M2 polarization and local proliferation of adipose tissue macrophages in obesity
The mass spectrometry proteomics data has been deposited to the ProteomeXchange Consortium (Deutsch et al., 2022) via the PRIDE (Perez-Riverol et al., 2019) partner repository with the dataset identifier PXD063718
is optionally used