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Influence of Exercise Increases in muscle carnosine content have been hypothesized to be an adaptation to long-term high-intensity training as demonstrated by higher values in bodybuilders (63) and trained sprinters (64)

Their findings revealed that astragaloside IV (AS-IV) increased Sirt1/Nrf2 activity, ultimately resulting in increased GPX4 expression, which decreased retinal lipid peroxidation

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