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In the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial, comparing tamoxifen or anastrozole to the combination of anastrozole and tamoxifen in postmenopausal women with early breast cancer, the combination therapy arm was discontinued early as an efficacy benefit over tamoxifen therapy alone was not demonstrated

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NK1 engages with c-MET through the K1SEMA interaction, which is virtually identical to that utilized in the formation of the c-MET II/HGF I complex (Fig

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Oxygen therapies used both in the delivery room and during hospitalization, immature organ development, and inflammatory/infective complications make the condition of preterm birth vulnerable to tissue injury 111,112

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Under oxidative stress conditions such as high light or drought, AtSAL1 is partially inactivated in a redox-dependent manner

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