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doi: 10.4161/psb.6.6.15147 24 GhantaS.DattaR.BhattacharyyaD.SinhaR.KumarD.HazraS.et al

Fatty and fried foods Certain foods, especially those that are high in fat, can exacerbate [side effects], Isaacson adds

increase by ~50 mg every 12 weeks as tolerated

The 72-hour threshold is not an official manufacturer guideline it's a practical working limit based on how quickly bacterial growth can become concerning at typical room temperatures (2025C) even in the presence of benzyl alcohol