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Biomolecules (2021) 11:557

Nonetheless, current research on the antioxidant properties of Klotho has primarily focused on its function in obstructing the insulin/insulin-like growth factor-1 (IGF-1) signaling pathway, as well as its role in the activation of FOXO and Nrf2 proteins

Based on the content of water (~ 70%) in the skeletal muscle of HSB, the concentrations of creatine plus phosphocreatine in the skeletal muscle of HSB can be calculated to range from 130 to 165 mmol/L, which are about 3 times those in the skeletal muscle of growing pigs [31]

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