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The triterpenoid sapogenin (2alpha-OH-Protopanoxadiol) ameliorates metabolic syndrome via the intestinal FXR/GLP-1 axis through gut microbiota remodelling

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Supplementing with vitamin C is not toxic but may cause unpleasant side effects at high doses

When given at very high doses nicotinic acid and niacinamide are found unchanged in the urine, suggesting that the capacity to methylate them has been saturated.*[35] *Well discuss this metabolism and elimination in more detail in a subsequent article, focusing in part on what it might imply for dosing and the bodys elimination mechanisms