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The SURMOUNT trials showed that participants with higher baseline BMI often ended up at higher maintenance doses (12.5mg or 15mg), while those with lower baseline BMI sometimes achieved their goals at 7.5mg or 10mg

3, 2010, pp

Additionally, -glutamyl-transpeptidase uses magnesium as an enzyme activator (Arancibia-Hernndez et al., 2022)

Moreover, fructose, once activated to fructose-1-phosphate, can also serve as a substrate for aldolase B and has been shown to increase NKCC2 functional expression in the kidney (Reungjui et al., 2007), is linked to NKCC2 function