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GLP-1 Tirzepatide Improves Heart Health in Obesity-Related HFpEF: Key Findings from the CMR Substudy of the SUMMIT Trial Since the 1990s, the incidence of heart failure with preserved ejection fraction (HFpEF) has risen, especially among patients with obesity

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Oral semaglutide may have many benefits and pros, including: Weight reduction Long-term weight management Reduced impacts of obesity Easy-to-use liquid medication Convenient daily dose No need for injections or needles May aid in blood sugar regulation May suppress appetite and lower the frequency of hunger cues May slow the rate of digestion Using oral semaglutide with a fitness routine and nutritious diet may lead to weight loss if diet changes and exercise alone are unsuccessful

Others respond less robustly, even with optimal dose, diet, and exercise