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258 Additionally, TREM2 has emerged as a potential therapeutic target due to its potential role in early AD in modulating neuroinflammation, A plaque deposition, and cognitive abilities

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Fatigue during GLP-1 therapy is usually temporary, with most patients experiencing significant improvement between weeks 3 and 6 of consistent use

and for those EGRIFTAtreated patients completing the 26-week treatment period that were re-randomized to EGRIFTA (T-T group) or re-randomized to placebo, 49% and 51%, respectively, had impaired glucose tolerance, while 4% re-randomized to EGRIFTA and 13% re-randomized to placebo had diet-controlled diabetes mellitus