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Atherosclerosis markers that were examined only in one study and therefore could not be meta-analyzed included resistin (4.00 [15.84, 7.84]

Classic examples include native GLP-1, which has a plasma half-life of approximately 2 minutes and required continuous infusion in early studiesan impractical route for chronic therapyyet was subsequently transformed into a once-weekly therapeutic through lipidation and albumin-binding strategies ( Third, pleiotropic signaling that aligns with physiological function rather than nonspecific toxicity favors re-evaluation

Ramracheya, R

"Best Practices for Peptide Storage in Research and Clinical Settings." Pharmaceutical Research , 41(2), 245-258