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note in Nature Medicine , NNMT inhibition has been shown to enhance energy expenditure and promote fat loss, even without dietary modification (Kraus et al., Nature Medicine )

Methionine plays a critical role in the metabolism, inositol stimulates the removal of fat from the liver to prevent fat storage, and choline prevents cholesterol and fat build up in the body

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Pregnant or breastfeeding women, individuals with active malignancy, and those with bleeding disorders should not use BPC-157