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Which is more suitable for a patient with neuroinflammatory conditions, including anxiety, depression, and Attention Deficit Hyperactivity Disorder (ADHD), semaglutide (GLP-1 receptor agonist) or tirzepatide, considering their potential anti-inflammatory effects and safety profiles?

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Starting with a low dose (0.25 mg per week) and following a gradual titration schedule significantly reduces the intensity and duration of gastrointestinal side effects compared to faster dose escalation

A 17% Reduction in Overall Cancer Risk A landmark study published in JAMA Oncology (Dai H et al., August 2025), drawing on data from 14 health systems encompassing approximately 20 million patients, found that adults with obesity who were prescribed GLP-1 receptor agonists had a 17% lower risk of developing cancer compared to carefully matched non-users