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H-2 Blockers (Tagamet, Pepcid, Zantac, etc) deplete calcium, chromium, folic acid, vitamin B12, and zinc

57 SeiwerthS.RucmanR.TurkovicB.SeverM.KlicekR.RadicB.et al (2018)

Consistent with these data, we found that rotenone inhibited mTOR-mediated p70S6K and 4E-BP1 activity and triggered neuronal apoptosis, as detected by increased expression of cleaved-caspase-3 in vivo (Fig