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Gastrointestinal side effects, particularly nausea and vomiting, can impair nutritional intake and medication continuation, potentially slowing progress

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The strength of our findings lies in the use of two distinct injury models: LPS, which induces Toll-like receptor 4 (TLR4)-mediated acute inflammation mimicking bacterial pneumonia, and papain, which simulates protease-mediated epithelial injury and allergic-type inflammation

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