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Cell Survival and Regeneration Beyond growth and repair, IGF-1 LR3 exhibits anti-apoptotic properties , helping prevent programmed cell death under stress conditions such as intense training or injury (Duan, Journal of Endocrinology )

HDAC inhibition can result in enhanced programmed cell death of tumor cells

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For example, liraglutide (LEADER trial), injectable semaglutide (SUSTAIN-6), dulaglutide (REWIND), and high-dose semaglutide (SELECT) have shown cardiovascular risk reduction in their respective clinical trials