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doi: 10.1111/obr.13543

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Research Applications Obesity and severe obesity treatment research Type 2 diabetes management studies Metabolic syndrome and cardiometabolic disease research Metabolic dysfunction-associated steatohepatitis (MASH) studies Triple incretin/glucagon receptor agonist research Energy expenditure and thermogenesis studies Hepatic fat metabolism and NAFLD research Body composition and weight loss research Cardiovascular risk reduction studies Multi-agonist peptide therapeutic research Appetite regulation and satiety research Glucose homeostasis and insulin sensitivity studies Safety Profile Retatrutide is currently in late-stage clinical development with ongoing safety evaluation through comprehensive Phase 3 trials, but existing Phase 1 and Phase 2 data provide substantial information about its safety profile