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Identifying GLP-1 Non-Responders Early in Treatment Early identification of patients who may not respond adequately to GLP-1 receptor agonist therapy represents a critical step in optimizing obesity treatment pathways

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Exosomes derived from synovial mesenchymal stem cells (MSCs) of patients with RA, which exhibit highlevel expression of miR146a, can specifically target and IL17mediated proinflammatory signals and TLR pathways, thereby reducing the invasiveness of synovial fibroblasts [454]