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What's next for GLP-1 innovation: A primer on the race reshaping pharma and chronic disease care Brandon Aylward Oct 16, 2025 10 min read Few categories in modern medicine have captured the imagination of patients, physicians, and investors as quickly as GLP-1 receptor agonists (GLP-1s)

Rare postmarketing reports of intestinal obstruction have also been noted

Tirzepatide, a newer GLP-1/GIP dual agonist, and retatrutide, a triple agonist still in trials, have pushed results even further, with average weight loss approaching 2025% of body weight

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