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Wound Healing, Skin Repair, and Regeneration Research A multicenter, randomized, evaluator-blinded, placebo-controlled study in diabetic neuropathic ulcers reported greater median plantar-ulcer closure with topical glycyl-L-histidyl-L-lysine copper gel compared with vehicle, 98.5% versus 60.8%, and lower ulcer infection incidence, 7% versus 34% [3]

Regenerative strategies aim to restore the structure and function of the gut itself

Initial research focused on its role in wound healing and tissue remodeling, where it was found to modulate the expression of extracellular matrix (ECM) proteins such as collagen and elastin