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Iodides also are used as adjunctive therapy before emergency nonthyroid surgery, if beta blockers are unable to control the hyperthyroidism, and to reduce gland vascularity before surgery for Graves disease.9 Iodides are not used in the routine treatment of hyperthyroidism because of paradoxical increases in hormone release that can occur with prolonged use

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Murali and Jayakumar, 2023

Once maintenance doses were reached, gastrointestinal symptoms typically stabilized at more manageable levels