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These models allow for transmigration studies as well as more precise measurements of TEER making them very useful in permeability studies and reduces the number of cells needed for the model [117]
doi: 10.1038/sj.bjp.0706912 123 BrhlHCihakJPlachJKunz-SchughartLNiedermeierMDenzelAet al
NAD + metabolism in neurodegenerative disorders Neurodegenerative diseases are a heterogeneous group of diseases, including Alzheimers disease (AD), Parkinsons disease (PD) and amyotrophic lateral sclerosis (ALS), which are characterized by progressive degeneration of the structure and function of the peripheral and central nervous system, with the characteristics like the accumulation of misfolded and aggregated proteins that are associated with severe proteotoxic stress (Fig
Immediately after differentiation, rinse the sections in running distilled water for 3 min to stop the differentiation
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