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Month 36 What to expect: Consistent weight loss: 410 lbs per month Medication reaches its optimal effect Lifestyle habits have a bigger impact Clothes fit differently Belly fat, back fat, and face puffiness reduce Plateaus may happen, but usually resolve with dosing or nutrition adjustments This is the stage where visible body changes are the most noticeable

10.1210/clinem/dgab931 74 MuriR.RummelC.McKinleyR.RebsamenM.Maissen-AbgottsponS.KreisR.et al (2024)

Fat Loss Reduces Insulation Losing weight, particularly rapid fat loss, results in reduced insulation and reduced protection from environmental cold

In the population of individuals aged 5059 years, arterial hypertension and hypercholesterolaemia coexist in nearly half of the patients (46.2%)