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Zanoni et al., 2019)

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Consistency in your chosen area can improve absorption and comfort, but rotating within that area helps reduce irritation and prevent lipodystrophy (changes in fat tissue under the skin)

The utility of LNPs has been further expanded by Andrew Tsourkas team, who employed them to deliver protein-based bifunctional degraders (bioPROTACs), thereby overcoming the membrane permeability limitations of small-molecule PROTACs and achieving TPD within subcellular compartments like mitochondria and the nucleus [188]