In phase 3 trials, lecanemab and donanemab slowed clinical decline in early Alzheimers by roughly a quarter to a third over eighteen months, with a known risk of amyloid-related brain swelling and small bleeds
Mller F, Dolder PC, Schmidt A, Liechti ME, Borgwardt S
PubMed Sikiric, P., Separovic, J., Anic, T., Buljat, G., Mikus, D., Seiwerth, S., Grabarevic, Z., Stancic-Rokotov, D., Pigac, B., Hanzevacki, M., Marovic, A., Rucman, R., Petek, M., Ziger, T., Sebecic, B., Zoricic, I., Turkovic, B., Aralica, G., Perovic, D., Duplancic, B., Lovric-Bencic, M., & Rotkvic, I
Seiwerth S, Milavic M, Vukojevic J, Gojkovic S, Krezic I, Vuletic LB, Pavlov KH, Petrovic A, Sikiric S, Vranes H, Prtoric A, Zizek H, Durasin T, Dobric I, Staresinic M, Strbe S, Knezevic M, Sola M, Kokot A, Sever M, Lovric E, Skrtic A, Blagaic AB, Sikiric P