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Common side effects (usually temporary): Nausea (most frequent, especially after injections) Constipation or loose stools Fatigue and low energy in the first few weeks Reduced appetite (this is also the intended effect) Injection site reactions Less common but serious: Pancreatitis (seek care immediately if you have severe abdominal pain) Gallbladder problems Changes in heart rate Rare thyroid concerns (see contraindications above) Staying well hydrated is important throughout treatment

Biomarkers can help quantify risk, track response, and support individualized nutrition planning (precision nutrition), but the field is still working out which markers truly improve outcomes beyond standard guidance

Endocrinologists doctors who treat hormone-related problems, including obesity and type 2 diabetes

J Clin Exp Cardiol 2012