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Cyanocobalamin is added as nutritional support, as B12 deficiency risk may increase with GLP-1-mediated dietary restriction and reduced intrinsic factor-dependent absorption

Voretigene neparvovec-rzyl (Luxturna) was approved by FDA in December of 2017 and is an adeno-associated virus vector-based gene therapy indicated for the treatment of patients with confirmed biallelic RPE65 mutation-associated retinal dystrophy

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