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The most commonly affected area is the terminal ileum (ileitis or regional enteritis), but the disease frequently extends into the colon (ileocolitis)

Details of diagnosis and procedure codes used for creating the two cohorts are included in the supporting information

Patients receiving long-term therapy with omeprazole or other proton pump inhibitors (PPIs) should be monitored for signs of B12deficiency

Batch Tested for Purity, Identity, and Stability Batch-level testing using techniques such as HPLC and mass spectrometry provides verifiable confirmation that what is labeled on the vial matches what is inside it