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Tirzepatide (marketed as Mounjaro and Zepbound) is a first-in-class dual GIP/GLP-1 receptor agonist developed by Eli Lilly that has demonstrated the largest body weight reductions of any approved anti-obesity pharmacotherapy, with up to 20.9% mean weight loss in clinical trials

However, when the intervals were increased to 48 and 72 hours, the murine models appeared to have reached a higher body weight and length compared to those that were given a placebo, but they still did not achieve full growth normalization

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