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GLP-1, GIP, and exenatide seem to have the same patterns here: Phe 22 is centered to specifically interact with the receptor and the adjacent hydrophobic residues of positions 23, 25, and 26 are used to form a hydrophobic region
Researchers had not previously examined whether GLP-1 medications might reduce the risk of substance use disorders more broadly or whether they could also lower the risk of serious outcomes such as overdose and drug-related death
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