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Within minutes, GHK-Cu is absorbed and circulating through the bloodstream, where it can reach skin, hair follicles, joints, and connective tissue throughout the body exactly the kind of broad, systemic distribution that GHK-Cus mechanisms of action call for

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Collagen and Extracellular Matrix Synthesis: GHK-Cu stimulates the production of collagen types I, III, and V by fibroblasts

S-adenosylmethionine regulates MAT1A and MAT2A gene expression in cultured rat hepatocytes: a new role for S-adenosylmethionine in the maintenance of the differentiated status of the liver