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There is no single cure, and both approaches can play a role in helping patients manage their weight

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The weight loss pattern continued, and participants lost an average of 14.9% of their body weight after 68 weeks

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Mechanistically, GLP-1R activation appears to downregulate TNF- production via 1-adrenergic, -opioid, and -opioid receptor pathways (Wong et al., 2024)

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Up to 25% of GLP-1 users stopped using insulin within 52 weeks of beginning GLP-1 treatment

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