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Short communication: metformin reduces CD4 T cell exhaustion in HIV-infected adults on suppressive antiretroviral therapy

Pros: FDA approved for weight loss Weekly injection is easy to keep up with Helps many patients lose weight steadily Can support blood sugar control Often reduces cravings significantly Cons: Nausea is common during the first weeks Weight regain may happen after stopping Some patients experience diarrhea or constipation Without insurance, costs may add up quickly 3