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[PubMed] [Google Scholar] 14.Fisher EJ, Adams BB

506 However, clinical trials for C9ORF72-targeted therapies WVE-004 and Tadnersen (IONIS-BIIB5Rx) have been terminated due to poor efficacy

Clinical Chemistry, 2009, 55(7): 1277-1279

4.1.3 Regulation of KARs by channel blockers Positively charged polyamine molecules are ubiquitously present in bacterial, plant, and animal cells and frequently function as blockers of cation-selective ion channels (Tabor and Tabor, 1984)