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Co-administration of selenium nanoparticles and metformin abrogate testicular oxidative injury by suppressing redox imbalance, augmenting sperm quality and nrf2 protein expression in streptozotocin-induced diabetic rats

(2014) 9:e101223

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They also had increased oxidative stress, demonstrated by higher levels of glutathione peroxidase (GPx), lipid peroxidation products (MDA), protein oxidation, and superoxide anions in both cortex and hippocampus in this group