A tricky thing with semaglutide is that GI symptoms (such as nausea, vomiting, and diarrhea) are the most common side effectsand each one can dehydrate you, indirectly contributing to fatigue
There is a growing body of evidence to support the notion that DMF/MMF may also exert effects on granulocytes and non-immune cell lineages, including keratinocytes and endothelial cells
Nature 509(7498):105109 Mancias JD, Pontano Vaites L, Nissim S, Biancur DE, Kim AJ, Wang X et al (2015) Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis
As a result, patients often report: Reduced cravings Better portion control Fewer blood sugar crashes Sustained fat loss over time Clinical trials have shown that many patients lose 1520% of their body weight when semaglutide is combined with lifestyle changes