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Simultaneously, MG modifications can also alter the electrically charged properties of histones, thereby weakening their binding strength to DNA, affecting the DNA-binding efficiency of transcription factors, and activating or inhibiting the expression of genes associated with carcinogenesis (48)

PMID: 24680856 [PubMed indexed for MEDLINE] Related Posts Articles This review explains that the lumbar intervertebral disc high-intensity zone, or HIZ, is an important MRI marker of lumbar disc degeneration and discogenic low back

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