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There are a few different types of weight loss drugs that have similar effects, but they may target slightly different receptors or may do so in a different way
The consequences of these modifications are that IGF-1 LR3 retains the pharmacological activity of IGF-1 as an agonist of the IGF-1 receptor, has very low affinity for the insulin-like growth factor-binding proteins (IGFBPs), and has improved metabolic stability resulting in approximately three times greater potency than IGF-1, with a significantly longer half-life of about 2030 hours relative to IGF-1s half-life of about 1215 hours
Some studies suggest that chronic use of GH secretagogues such as ipamorelin could potentially increase the risk of certain diseases, reduce lifespan, or accelerate cellular aging processes, although these observations are preliminary
[DOI] [PMC free article] [PubMed] 447.Krug HF, Nau K
