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Its aim is to prove that a drug substance which is exposed to light does not undergo unacceptable changes (ICH 1996)resulting not only in loss of activity (degradation) but also in the formation of radicals, energy transfer, or luminescence, which may lead to severe side effects, whose cause could be for example light-induced reaction with endogenous substances (Tonnesen 2004)

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When investigated as a therapeutic following induction of asthma, pterostilbene significantly ameliorated disease severity, explained by the decrease in elevation of lymph node, splenic and pulmonary CD4+IL-4+T cells, decrease in serum IL-13, IgE and IgG levels, and reduction in pulmonary eosinophil infiltration [207]

Microneedling with PRF Masque & Injections PRF, Platelet-Rich Fibrin, will be drawn from designated area, and placed on face as masque or injections