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Typical findings may include: Low hemoglobin Low hematocrit Elevated mean corpuscular volume (MCV) Enlarged red blood cells General laboratory ranges often include: Serum folate below 2 ng/mL may indicate deficiency Serum vitamin B12 below 200 pg/mL may indicate deficiency Additional testing may be recommended when results fall into borderline ranges

In any given case, the onset and progression of ADRD may be driven by one or several interacting mechanisms discussed below, including inflammation and oxidative stress, alterations in cerebral metabolism, cerebral perfusion, systemic and cerebrovascular structure and function, and blood-brain barrier integrity

It is worth exploring whether network pharmacology can be used to predict potential core targets of natural polysaccharides, and if the signalling pathway of significant enrichment of core targets can be used as the research pathway